When your immune system detects an unsafe substance or receives indications of a disease, it activates a protein in the complement framework and attacks the foreign body. In this way, proteins are activated as a chain reaction to reinforce the resistance. In medical terms, it is known as a complement overflow. The proteins, such as C3, are consumed in this cycle. Learn to know about C3 test?
C3 proteins are essential for the complement system, which is vital for your immune system. The complement system comprises an excess of 30 separate proteins, and they cooperate in a group to shield you from disease and sickness.
Proteins in the complement system have many roles, including:
● it assists your immune system with making antibodies (proteins that answer apparent microbes) and makes antibodies more successful.
● assists your body with disposing of dead cells and other waste.
● kills infections (makes them less destructive).
● perceives and kills infections, microorganisms, and different microbes.
● works with various elements of the immune system to assist them with eliminating microscopic organisms.
In some cases, complement proteins like C3 mistakenly attack and kill tissues that aren’t harmful. Immune system afflictions make the body accept that its tissues are unfamiliar and harmful. The complement system answers by producing antibodies to battle its tissues.
What is this test?
This test assesses how many C3 proteins are in your blood. These proteins are essential for your complement system. The C3 protein is a significant component of your immune system and helps kill microorganisms and infections that cause sickness.
The C3 protein is the most critical and abundant in the complement system, and it covers organisms to destroy them. The test estimates complement C3 levels and how they compare with other components of the complement system. With these details, your doctor can analyze and plan the treatment for specific infections. One of the infections that frequently cause unusual C3 is systemic lupus erythematosus (SLE). Lupus is an immune system disorder.
Why do I need this test?
You might require this test if your doctor suspects you might have lupus or another immune system sickness. Side effects of lupus might include:
● Rash looking like a butterfly across your cheeks
● Mouth or nose ulcers
● Hair loss
● Light sensitivity
● Joint pain and swelling
● Excessive sleepiness
● Pain in your chest while breathing profoundly
You may likewise have the test in the possibility of getting repeated bacterial diseases. Also, if your doctor suspects an immune system illness, you might be advised to have this test to keep track of its development.
What do my test results say?
Test results might vary depending on age, gender, and health history. Your test outcomes might be different depending on the lab. Ask your doctor what your test outcomes mean for you.
The common range for a complement C3 blood test is 75 to 175 milligrams/deciliter (mg/dL), or 0.75 to 1.75 (g/L).
Complement levels may shoot up soon after a disease or injury. When your complement system responds to the current illness, like lupus, levels typically decrease.
You can develop a lack in your complement C3. If your C3 complement level is low and any remaining complement parts are normal, it’s generally a direct result of a lack of acquired parts. It may indicate specific immune system problems.
Frequently you may have low levels of a few complement parts. It is the consequence of acquired infection. In the case that your C3 and C4 levels are decreased, it may indicate that you have lupus. Low C3 and C4 levels may likewise be an indication of alcoholic liver sickness.
Different circumstances connected to low C3 levels include:
● C3 deficiency, a condition that causes intermittent bacterial contaminations
● Various types of kidney infection
Assuming you are being treated for illnesses like lupus and your complement C3 and C4 levels go up, it is typically a sign that your therapy is working.
How is the C3 test done?
A blood sample is taken for the C3 test. A needle is used to extract blood from your vein. The test is not painful; it just feels like a little prick where the needle was inserted.
Your doctor may advise a C3 test based on a primary diagnosis and symptoms. Consult your doctor for an accurate interpretation of the test results to facilitate the diagnosis and plan the treatment accordingly.